--- a/tcpiohandler.cc
+++ b/tcpiohandler.cc
@@ -369,8 +369,10 @@ public:
     }
 
     if (s_users.fetch_add(1) == 0) {
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
       ERR_load_crypto_strings();
       OpenSSL_add_ssl_algorithms();
+#endif
       openssl_thread_setup();
 
       s_ticketsKeyIndex = SSL_CTX_get_ex_new_index(0, nullptr, nullptr, nullptr, nullptr);
@@ -439,6 +441,7 @@ public:
     d_tlsCtx.reset();
 
     if (s_users.fetch_sub(1) == 1) {
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
       ERR_free_strings();
 
       EVP_cleanup();
@@ -448,6 +451,7 @@ public:
       CONF_modules_unload(1);
 
       CRYPTO_cleanup_all_ex_data();
+#endif
       openssl_thread_cleanup();
     }
   }