diff --git a/lang/python/python3/patches/030-bpo-43112-detect-musl-as-a-separate-SOABI-GH-24502.patch b/lang/python/python3/patches/030-bpo-43112-detect-musl-as-a-separate-SOABI-GH-24502.patch
new file mode 100644
index 000000000..f22075e26
--- /dev/null
+++ b/lang/python/python3/patches/030-bpo-43112-detect-musl-as-a-separate-SOABI-GH-24502.patch
@@ -0,0 +1,75 @@
+From 3f79de7b8411c76a1fcd1ca850ea62500be7a881 Mon Sep 17 00:00:00 2001
+From: Natanael Copa <ncopa@alpinelinux.org>
+Date: Sat, 29 Jan 2022 00:02:54 +0100
+Subject: [PATCH 1/2] bpo-43112: detect musl as a separate SOABI (GH-24502)
+MIME-Version: 1.0
+Content-Type: text/plain; charset=UTF-8
+Content-Transfer-Encoding: 8bit
+
+musl libc and gnu libc are not ABI compatible so we need set different
+SOABI for musl and not simply assume that all linux is linux-gnu.
+
+Replace linux-gnu with the detected os for the build from config.guess
+for linux-musl*.
+
+(cherry picked from commit 1f036ede59e2c4befc07714cf76603c591d5c972)
+Signed-off-by: Šimon Bořek <simon.borek@nic.cz>
+---
+ Lib/test/test_sysconfig.py                                | 8 ++++----
+ .../next/Build/2021-02-10-17-54-04.bpo-43112.H5Lat6.rst   | 1 +
+ configure                                                 | 5 +++++
+ configure.ac                                              | 5 +++++
+ 4 files changed, 15 insertions(+), 4 deletions(-)
+ create mode 100644 Misc/NEWS.d/next/Build/2021-02-10-17-54-04.bpo-43112.H5Lat6.rst
+
+--- a/Lib/test/test_sysconfig.py
++++ b/Lib/test/test_sysconfig.py
+@@ -425,11 +425,11 @@ class TestSysConfig(unittest.TestCase):
+             self.assertTrue('linux' in suffix, suffix)
+         if re.match('(i[3-6]86|x86_64)$', machine):
+             if ctypes.sizeof(ctypes.c_char_p()) == 4:
+-                self.assertTrue(suffix.endswith('i386-linux-gnu.so') or
+-                                suffix.endswith('x86_64-linux-gnux32.so'),
+-                                suffix)
++                expected_suffixes = 'i386-linux-gnu.so', 'x86_64-linux-gnux32.so', 'i386-linux-musl.so'
+             else: # 8 byte pointer size
+-                self.assertTrue(suffix.endswith('x86_64-linux-gnu.so'), suffix)
++                expected_suffixes = 'x86_64-linux-gnu.so', 'x86_64-linux-musl.so'
++            self.assertTrue(suffix.endswith(expected_suffixes),
++                            f'unexpected suffix {suffix!r}')
+ 
+     @unittest.skipUnless(sys.platform == 'darwin', 'OS X-specific test')
+     def test_osx_ext_suffix(self):
+--- /dev/null
++++ b/Misc/NEWS.d/next/Build/2021-02-10-17-54-04.bpo-43112.H5Lat6.rst
+@@ -0,0 +1 @@
++Detect musl libc as a separate SOABI (tagged as ``linux-musl``).
+\ No newline at end of file
+--- a/configure
++++ b/configure
+@@ -5376,6 +5376,11 @@ EOF
+ 
+ if $CPP $CPPFLAGS conftest.c >conftest.out 2>/dev/null; then
+   PLATFORM_TRIPLET=`grep -v '^#' conftest.out | grep -v '^ *$' | tr -d ' 	'`
++  case "$build_os" in
++  linux-musl*)
++    PLATFORM_TRIPLET=`echo "$PLATFORM_TRIPLET" | sed 's/linux-gnu/linux-musl/'`
++    ;;
++  esac
+   { $as_echo "$as_me:${as_lineno-$LINENO}: result: $PLATFORM_TRIPLET" >&5
+ $as_echo "$PLATFORM_TRIPLET" >&6; }
+ else
+--- a/configure.ac
++++ b/configure.ac
+@@ -866,6 +866,11 @@ EOF
+ 
+ if $CPP $CPPFLAGS conftest.c >conftest.out 2>/dev/null; then
+   PLATFORM_TRIPLET=`grep -v '^#' conftest.out | grep -v '^ *$' | tr -d ' 	'`
++  case "$build_os" in
++  linux-musl*)
++    PLATFORM_TRIPLET=`echo "$PLATFORM_TRIPLET" | sed 's/linux-gnu/linux-musl/'`
++    ;;
++  esac
+   AC_MSG_RESULT([$PLATFORM_TRIPLET])
+ else
+   AC_MSG_RESULT([none])
diff --git a/lang/python/python3/patches/131-configure_ac-switch-PLATFORM_TRIPLET-suffix-to-musl.patch b/lang/python/python3/patches/131-configure_ac-switch-PLATFORM_TRIPLET-suffix-to-musl.patch
new file mode 100644
index 000000000..dfe8e06fe
--- /dev/null
+++ b/lang/python/python3/patches/131-configure_ac-switch-PLATFORM_TRIPLET-suffix-to-musl.patch
@@ -0,0 +1,49 @@
+From 15d512cc35106392ed7583d0e000d9a1b865f1e1 Mon Sep 17 00:00:00 2001
+From: =?UTF-8?q?=C5=A0imon=20Bo=C5=99ek?= <simon.borek@nic.cz>
+Date: Mon, 27 Jun 2022 13:53:37 +0200
+Subject: [PATCH 2/2] configure.ac: switch PLATFORM_TRIPLET suffix to '-musl'
+ based on `host_os` instead of `build_os`
+
+As `build_os` and `host_os` are results of autoconf's `AC_CANONICAL_BUILD`
+and `AC_CANONICAL_HOST` macros[^1], the former refers to the system running the build
+and the latter to the system that will run the compiled program.
+
+`PLATFORM_TRIPLET` should refer to the target platform when cross-compiling.
+Its libc related part should be therefore derived from the target platform as well
+- which is currently not the case - `PLATFORM_TRIPLET` '-gnu' suffix is/isn't switched to '-musl'
+based on `build-os` rather than `host-os` which leads to error message[^2]
+and build failure when compiling Python on glibc system for musl target.
+
+[^1]: https://www.gnu.org/software/autoconf/manual/autoconf-2.68/html_node/Canonicalizing.html ,
+https://www.gnu.org/software/autoconf/manual/autoconf-2.68/html_node/Specifying-Target-Triplets.html
+[^2]: "internal configure error for the platform triplet, please file a bug report"
+
+Co-authored-by: Pali Rohár <pali@kernel.org>
+Signed-off-by: Šimon Bořek <simon.borek@nic.cz>
+---
+ configure    | 2 +-
+ configure.ac | 2 +-
+ 2 files changed, 2 insertions(+), 2 deletions(-)
+
+--- a/configure
++++ b/configure
+@@ -5376,7 +5376,7 @@ EOF
+ 
+ if $CPP $CPPFLAGS conftest.c >conftest.out 2>/dev/null; then
+   PLATFORM_TRIPLET=`grep -v '^#' conftest.out | grep -v '^ *$' | tr -d ' 	'`
+-  case "$build_os" in
++  case "$host_os" in
+   linux-musl*)
+     PLATFORM_TRIPLET=`echo "$PLATFORM_TRIPLET" | sed 's/linux-gnu/linux-musl/'`
+     ;;
+--- a/configure.ac
++++ b/configure.ac
+@@ -866,7 +866,7 @@ EOF
+ 
+ if $CPP $CPPFLAGS conftest.c >conftest.out 2>/dev/null; then
+   PLATFORM_TRIPLET=`grep -v '^#' conftest.out | grep -v '^ *$' | tr -d ' 	'`
+-  case "$build_os" in
++  case "$host_os" in
+   linux-musl*)
+     PLATFORM_TRIPLET=`echo "$PLATFORM_TRIPLET" | sed 's/linux-gnu/linux-musl/'`
+     ;;