diff --git a/lang/python/python3/patches/002-fix-blake2-detection.patch b/lang/python/python3/patches/002-fix-blake2-detection.patch
index 72b6ea219..88916af07 100644
--- a/lang/python/python3/patches/002-fix-blake2-detection.patch
+++ b/lang/python/python3/patches/002-fix-blake2-detection.patch
@@ -5,7 +5,7 @@
  #endif
  
 -#ifdef NID_blake2b512
-+#ifndef OPENSSL_NO_BLAKE2
++#if defined(NID_blake2b512) && !defined(OPENSSL_NO_BLAKE2)
  #define PY_OPENSSL_HAS_BLAKE2 1
  #endif